KJCAB, Volume 1, Issue 1, July 2021
Articles

Association of Demographic Details with the Onset of Precancerous Lesions in Bengaluru Population

Shweta Sharma
Department of Life Sciences, Kristu Jayanti College, Autonomous, Bengaluru
Karishma Jain
Department of Biochemistry, School of Sciences, Jain (Deemed University), Bengaluru
Dilip N.
Department of Biochemistry, School of Sciences, Jain (Deemed University), Bengaluru
Puneet Shetty
Indian Cancer Society, Bengaluru
Chethana T.
Indian Cancer Society, Bengaluru

Published 2021-07-26

Keywords

  • Leukoplakia, Demographic, Oral Carcinogenesis.

How to Cite

Sharma, S. ., Jain, K. ., N., D. ., Shetty, P. ., & T., C. . (2021). Association of Demographic Details with the Onset of Precancerous Lesions in Bengaluru Population. Kristu Jayanti Journal of Core and Applied Biology (KJCAB), 1(1), 22–27. https://doi.org/10.59176/kjcab.v1i1.2171

Abstract

Oral cancer is among the top three types of cancers in India. In India, 90-95 % of the oral cancers is squamous cell carcinoma. The mortality due to oral cancer is increasing in a high rate in India. There are many contributing factors which increase the incidence of oral pre-cancer and cancer. Therefore, this study analyzed the correlation between various demographic characters with the onset of oral lesions (leukoplakia). In the present study, total of 80 subjects with oral leukoplakia were included from Indian Cancer Society organized camps in different region of Bangalore city. The respondent was personally interviewed and collected the data. The demographic data includes education, alcohol addiction, tobacco intake, sexual activity etc. Interestingly, the result obtained after statistically test found positive correlation between demographic details and oral leukoplakia. Socioeconomic status, brushing number, alcohol, tobacco, poor oral hygiene (p<0.01) emerge out as a major contributing risk factors for the pathogenesis of oral lesions.The demographic characteristics of Bangalore population concurred with oral pre-cancer (leukoplakia) were found to be smokeless tobacco, alcohol, poor hygiene, and caffeinated drinks. Hence, awareness among the population about the resulted contributing factors would help to reduce the occurrence of oral carcinogenesis.

Downloads

Download data is not yet available.

References

  1. Al-Dakkak (2010). Tea, coffee and oral cancer risk. Can-cer Epidemiol Biomarkers Prev. 19: 1723–1736.
  2. Bánóczy J1, Gintner Z, Dombi C (2001). Tobacco use and oral leukoplakia, J Dent Educ. 65(4): 322-7. DOI: https://doi.org/10.1002/j.0022-0337.2001.65.4.tb03402.x
  3. CH Lee, YC Ko, HL Huang, YY Chao, CC Tsai, TY Shieh, LM Lin (2003). The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral sub-mucous fibrosis in southern Taiwan. British Journal of Cancer. 88: s366–372. DOI: https://doi.org/10.1038/sj.bjc.6600727
  4. Douglas EM, Walter JP, Ellen E (2007). Smoking and drinking in relation to oral cancer and oral epi-thelial dysplasia. Cancer Causes and Control. 18(9):919-29. DOI: https://doi.org/10.1007/s10552-007-9026-4
  5. Johnson N ( 2001). Tobacco use and oral cancer: a glob-al perspective. J Dent Educ. 65(4):328-39. DOI: https://doi.org/10.1002/j.0022-0337.2001.65.4.tb03403.x
  6. Kamal N, Faheem M, Mohammad A (2017). Smokeless tobacco (paan and gutkha) consumption, preva-lence, and contribution to oral cancer. 39:Article ID: e2017009. DOI: https://doi.org/10.4178/epih.e2017009
  7. Ken Russell Coelho (2012), Challenges of the Oral Can-cer Burden in India. Journal of Cancer Epidemi-ology. 2012: 701932 . DOI: https://doi.org/10.1155/2012/701932
  8. Pemberton MN (2018), Oral cancer and tobacco: devel-opments in harm reduction, British Dental Jour-nal. 225: 822–826 DOI: https://doi.org/10.1038/sj.bdj.2018.928
  9. Mahendra PS,Vijay Kumar,Akash Agarwal,Rajendra Kumar, MLB Bhatt, and Sanjeev Misra (2016). Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India, J Oral BiolCraniofac Res. 6(1): 31–34. DOI: https://doi.org/10.1016/j.jobcr.2015.11.002
  10. Marcione Aparecida de Souza Moura, Anke Bergmann, Suzana Sales de Aguiar, Luiz Claudio Santos Thuler (2014). The magnitude of the association between smoking and the risk of developing cancer in Brazil: a multicenter study, BMJ Open.4(2):e003736. DOI: https://doi.org/10.1136/bmjopen-2013-003736
  11. Pablo H. Montero, Snehal G. Patel (2015). Cancer of the oral cavity, Surg Oncol Clin N Am. 24(3): 491–508. DOI: https://doi.org/10.1016/j.soc.2015.03.006
  12. Park K (1994) Textbook of preventive and social medi-cine. 14th edition. Jabalpur: Banarsidas Bhanot Publishers
  13. Maher R, Lee AJ, Warnakulasuriya KA, Lewis JA, Johnson NW (1994). Role of areca nut in the causation of oral submucous fibrosis: a case‐control study in Pakistan. Journal of Oral Pathol-ogy and Medicine. 23(2): 65-69. DOI: https://doi.org/10.1111/j.1600-0714.1994.tb00258.x
  14. Sheetal VK, Surendra SS (2015). Smokeless tobacco use in Urban Indian women: Prevalence and predic-tors, Indian Journal of Medical and Paediatric Oncology, Indian J Med Paediatr Oncol. 36(3): 176–182. DOI: https://doi.org/10.4103/0971-5851.166739
  15. SreeVidya Krishna Rao, Gloria Mejia, Kaye Roberts-Thomson, Richard Logan (2012), Epidemiology of Oral Cancer in Asia in the Past Decade- An Update (2000-2012), Asian Pacific journal of cancer prevention : APJCP;10.7314/APJCP:14.10.5567 Varshitha (2015), Prevalence of Oral Cancer in India, A/J. Pharm. Sci. & Res;Vol. 7(10): 845-848.
  16. Walsh PM, Epstein JB(2000). The oral effects of smoke-less tobacco, J Can Dent Assoc. 66(1):22-5.
  17. Zygogianni AG, Kyrgias G, Karakitsos P, Psyrri A, Kouvaris J, Kelekis N, Kouloulias V( 2011). Oral squamous cell cancer: early detection and the role of alcohol and smoking. 186:1758-3284-3-2. DOI: https://doi.org/10.1186/1758-3284-3-2