Volume 3, Issue 2, December 2023
Original Research

Phytochemical Screening and Determination of Antioxidant and Antimicrobial Activity in Crude Extract of Annona muricata

PDF
  • Roopa Prasad,
  • CM Reena Josephine,
  • Pawan Kumar Jangid,
  • Satya Pavan,
  • Ujwal Reddy KS,
  • Anamika
Roopa Prasad
Department of Life Sciences, Kristu Jayanti College, Bengaluru, Karnataka 560077
CM Reena Josephine
Department of Life Sciences, Kristu Jayanti College, Bengaluru, Karnataka 560077
Pawan Kumar Jangid
Department of Life Sciences, Kristu Jayanti College, Bengaluru, Karnataka 560077
Satya Pavan
Department of Life Sciences, Kristu Jayanti College, Bengaluru, Karnataka 560077
Ujwal Reddy KS
Department of Life Sciences, Kristu Jayanti College, Bengaluru, Karnataka 560077
Anamika
Department of Life Sciences, Kristu Jayanti College, Bengaluru, Karnataka 560077
DOI: https://doi.org/10.59176/kjcab.v3i2.2381

Published 2024-08-14

Keywords

  • <i>Annona muricata</i>, Phytochemical studies, Antioxidant property, Antibacterial activity

How to Cite

Prasad, R., Josephine, C. R., Jangid, P. K., Pavan, S., KS, U. R., & Anamika. (2024). Phytochemical Screening and Determination of Antioxidant and Antimicrobial Activity in Crude Extract of <i>Annona muricata</i>. Kristu Jayanti Journal of Core and Applied Biology (KJCAB), 3(2), 41–45. https://doi.org/10.59176/kjcab.v3i2.2381
Crossref
Scopus
Google Scholar
Europe PMC

Abstract

Annona muricata (Linn) is a member of the Annonaceae family, which includes more than 2000 species and 119 genera. Although the plant is native to the warmest tropical regions of North and South America, it is currently widely distributed throughout the world's tropical and subtropical regions, including Nigeria, Malaysia, and India. A. muricata is an herbaceous plant whose leaves, bark, roots, fruits, and seeds are all utilized as natural cures for a range of ailments. The fruits and seeds have analgesic and antidiarrheal properties and are used to treat worm infestations and parasite diseases. The leaves, bark, and roots are utilized for their anti-effects that are sedative, antimalarial, antispasmodic, anti-inflammatory, and anticonvulsant. Secondary metabolites present in the plant exhibit strong anticancer effects and selective toxicity against a variety of malignant cells, without endangering healthy cells. The objective of the study was to identify the antioxidants and phytochemicals found in the leaves, seeds, and bark of A. muricata. The antibacterial property of the plant was examined using well diffusion method against different strains of microorganisms.

PDF

Downloads

Download data is not yet available.

References

  1. Agu KC, Okolie PN (2017). Proximate composition, phytochemical analysis, and in vitro antioxidant potentials of extracts of Annona muricata (Soursop). Food Sci. Nutr. 5:1029 - 1036.
  2. Agu KC, Okolie NP, Falodun A, Erharuyi O, Igbe I, Elekofehinti OO, Edosa RO, Oghagbon SE (2017). Isolation and elucidation of 15-acetylguanacone from Soursop (Annona muricata Linn) Fruit and Molecular docking experiments. J. Applied Sci. Environ. Manag. 21(2), 236 - 243.
  3. Atawodi S. Nigerian foodstuffs with prostate cancer chemopreventive polyphenols. Infect Agent Cancer, 6 (Suppl 2) (2011)
  4. Baskar R, Rajeswari V, Kumar, TS (2007). In vitro antioxidant studies in leaves of Annona species. Indian J. Exp. Biol. 45, 480 - 485.
  5. Coria-Tellez AV, Montalvo-Gonzalez E, Yahia EM, Obledo-Vazquez E N (2018). Annona muricata: A comprehensive review of its traditional medicinal uses, phytochemicals, pharmacological activities, mechanisms of action, and toxicity. Arabian J. Chem. 11(15): 662 691.
  6. De Sousa OV, Vieira GDV, de Pinho JDJ, Yamamoto CH, Alves MS (2010). Antinociceptive and antiinflammatory activities of the ethanol extract of Annona muricata L. leaves in animal models. Int. J. Mol. Sci. 11(5), 2067 - 2078.
  7. Edeoga HO, Gomina A (2000). Nutritional values of some nonconventional leafy vegetables of Nigeria. J. Econ. Taxon. Bot. 24:7 - 13.
  8. Harborne JB (1973). Phytochemical methods. London Chapman and Hall, Ltd, pp. 49-88.
  9. Hedge JE, Hofreiter BT (1962). In: Carbohydrate Chemistry, 17 (Eds. Whistler R.L. and Be Miller, J.N.), Academic Press, New York.
  10. Karou SD, Tchacondo T, Djikpo Tchibozo MA, AbdoulRahaman S, Anani K, Koudouvo K, Batawila K, Agbonon A, Simpore J, de Souza C (2011). Ethnobotanical study of medicinal plants used in the management of diabetes mellitus and hypertension in the Central Region of Togo. Pharm. Biol.49(12): 1286 - 97.
  11. Kossouoh C, Moudachirou M, Adjakidje V, Chalchat JC, Figueredo G (2007). Essential oil chemical composition of Annona muricata L. leaves from Benin. J.Essent. Oil Res. 19(4):307-309.
  12. Lowry OH, Rosebrough NJ, Farr AL. Randall RJ (1951). Protein measurement with the Folin phenol reagent. The Journal of Biological Chemistry. 193: 265 - 275.
  13. Monigatti M, Bussmann RW, Weckerle CS (2013). Medicinal plant use in two Andean communities located at different altitudes in the Bolivar Province, Peru. J Ethnopharmacol, 145 (2): 450-64.
  14. Magana MA, Gama LM, Mariaca R (2010). The use of medicinal plants in communities Maya-Chontales of Nacajuca, Tabasco, Mexico. Polibotnica, 29: 213-262.
  15. Mishra S, Ahmad S, Kumar N, Sharma BK (2013). Annona muricata (the cancer killer): A review. Glob. J. Pharm. Res. 2, 1613-1618.
  16. Moghadamtousi SZ, Fadaeinasab M, Nikzad S, Mohan G, Ali HM, Kadir HA (2015). Annona muricata (Annonaceae): A Review of Its Traditional Uses, Isolated Acetogenins and Biological Activities. Int. J. Mol. Sci. 16, 15625 - 15658.
  17. Mohammed Rasha N, Ramadhan Hanan H, Shari Falah H (2021). Hypoglycemic, Hypolipidemic, renal protective and antioxidant activity of Annona muricata in streptozotocin-induced diabetic rats. Res. J. Pharma. Technol. 14(12): 6484 - 6490.
  18. Neglo D, Tettey CO, Essuman EK, Amenu JD, MillsRobertson FC, Sedohia D, Boakye AA, Abaye DA. Evaluation of the Modulatory Effect of Annona muricata Extracts on the Activity of Some Selected Antibiotics against Biofilm-Forming MRSA. Evid Based Complement Alternat Med. 2021 Dec 20;2021:9342110.
  19. Padma P. (2001). Effect of Annona muricata and Polyalthia cerasoides on brain neurotransmitters and enzyme monoamine oxidase following cold immobilization stress. J. Natural Remedies; 1(2): 144-46.
  20. Satyanarayana T, 2006. Hypoglycemic and antihyperglycemic effect of alcoholic extract of Euphorbia leucophylla and its fractions in normal and in alloxan induced diabetic rats. Pharmacog Mag, 2:244-53.
  21. Samuel AJ, Kalusalingam A, Chellappan DK, Gopinath R, Radhamani S, Husain HA, Muruganandham V, Promwichit P (2010). Ethnomedical survey of plants used by the Orang Asli in Kampung Bawong, Perak, West Malaysia. J. Ethnobiol. Ethnomed. 7; 6:5.
  22. Shimada K, Fujikawa K, Yahara K and Nakamura T. (1992). Antioxidative properties of xanthan on the antioxidation of soybean oil in cyclodextrin emulsion. J Agricultur Food Chem. 40: 945 - 948.
  23. Sundarrao.1993. Preliminary screening of antibacterial and antitumor activities of Papua New Guinean native medicinal plants. Int. J. Pharmacog.1993;31(1):3-6
  24. Vandebroek I, Balick MJ, Ososki A, Kronenberg F, Yukes J, Wade C, et al. (2010). The importance of botellas and other plant mixtures in Dominican traditional medicine. J Ethnopharmacol, 128 (1): 20 - 41.
  25. Yen G, and Wu J. (1999). Antioxidant and radical scavenging properties of extract from Ganoderma tsugae. Food Chem. 65: 375 - 379.
  26. Zubaidi SN, Mohd Nani H, Ahmad Kamal MS, Abdul Qayyum T, Maarof S, Afzan A, Mohmad Misnan N, et al. (2023). A. Annona muricata: Comprehensive Review on the Ethnomedicinal, Phytochemistry, and Pharmacological Aspects Focusing on Antidiabetic Properties. Life (Basel). 28;13(2):353.

Most read articles by the same author(s)

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.